Can this be used with retinol? September 12, 2022 20:26 Updated Often, using salicylic acid and retinol at the same time can cause irritation. We would not recommend using both together. Related articles What is the pH of Pore Release? Can this be used all-over the face? Do you ship internationally? How do the ingredients function to soften gunk in blackheads so they can be released? Is the color artificial?