What do I do after I take off my patch? September 02, 2020 04:32 Updated First, wash your skin using a low pH-cleanser, followed by an exfoliator. After skin is dry, use a moisturizer to nourish your skin. Read more about post-patch care here. Related articles I used my patch overnight, but it didn’t work! What did I do wrong? What kind of pimple is Mighty Patch designed for? Can you send me free product to test in exchange for a review? How do I use Mighty Patch? What’s the difference between Mighty Patch Original, Invisible+ and Surface?