Safe to use while on Accutane? One month in. My skin isn’t extremely dry. September 17, 2020 22:48 We recommend you consult your doctor before using any prescription drugs with Mighty Patch. Related articles Can I use Differin underneath the patch? What's the maximum length of time I should wear a patch? Should I keep it on if the pimple/patch still hasn't gone white after six hours? It didn't work for me. Is it recommended or safe for sensitive skin? What is hydrocolloid?